The immunologic advantage of recurrent nasopharyngeal carcinoma from the viewpoint of Galectin-9/Tim-3-related changes in the tumour microenvironment

Given salvage treatment for recurrent nasopharyngeal carcinoma (NPC) remains a clinical dilemma, immunotherapy targeting NPC-specific immunosuppression may bring new hope. We analyzed the expression of CD8, CD4, Foxp3 and Tim-3 in lymphocytes, and of Galectin-9 in tumour cells between paired primary...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Chen, Tseng-Cheng, Chen, Chao-Hsien, Wang, Cheng-Ping, Lin, Pei-Hsuan, Yang, Tsung-Lin, Lou, Pei-Jen, Ko, Jenq-Yuh, Wu, Chen-Tu, Chang, Yih-Leong
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5583393/
https://ncbi.nlm.nih.gov/pubmed/28871094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10386-y
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