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Analysis of population-specific pharmacogenomic variants using next-generation sequencing data

Functional rare variants in drug-related genes are believed to be highly differentiated between ethnic- or racial populations. However, knowledge of population differentiation (PD) of rare single-nucleotide variants (SNVs), remains widely lacking, with the highest fixation indices, (F(st) values), f...

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Pubblicato in:Sci Rep
Autori principali: Ahn, Eunyong, Park, Taesung
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5583360/
https://ncbi.nlm.nih.gov/pubmed/28871186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08468-y
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