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Breast Cancer Spheroids Reveal a Differential Cancer Stem Cell Response to Chemotherapeutic Treatment

An abnormal multicellular architecture is a defining characteristic of breast cancer and, yet, most in vitro tumor models fail to recapitulate this architecture or accurately predict in vivo cellular responses to therapeutics. The efficacy of two front-line chemotherapeutic agents (paclitaxel and ci...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Reynolds, Daniel S., Tevis, Kristie M., Blessing, William A., Colson, Yolonda L., Zaman, Muhammad H., Grinstaff, Mark W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5583341/
https://ncbi.nlm.nih.gov/pubmed/28871147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10863-4
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