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EMBEDDED MULTICELLULAR SPHEROIDS AS A BIOMIMETIC 3D CANCER MODEL FOR EVALUATING DRUG AND DRUG-DEVICE COMBINATIONS

Multicellular aggregates of cells, termed spheroids, are of interest for studying tumor behavior and for evaluating the response of pharmacologically active agents. Spheroids more faithfully reproduce the tumor macrostructure found in vivo compared to classical 2D monolayers. We present a method for...

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Detaylı Bibliyografya
Asıl Yazarlar: Charoen, Kristie M., Fallica, Brian, Colson, Yolonda L., Zaman, Muhammad H., Grinstaff, Mark W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923358/
https://ncbi.nlm.nih.gov/pubmed/24360576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2013.11.038
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