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EMBEDDED MULTICELLULAR SPHEROIDS AS A BIOMIMETIC 3D CANCER MODEL FOR EVALUATING DRUG AND DRUG-DEVICE COMBINATIONS
Multicellular aggregates of cells, termed spheroids, are of interest for studying tumor behavior and for evaluating the response of pharmacologically active agents. Spheroids more faithfully reproduce the tumor macrostructure found in vivo compared to classical 2D monolayers. We present a method for...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3923358/ https://ncbi.nlm.nih.gov/pubmed/24360576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2013.11.038 |
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