TRIB3 inhibits proliferation and promotes osteogenesis in hBMSCs by regulating the ERK1/2 signaling pathway

Osteogenic differentiation in human bone marrow-derived mesenchymal stem cells (hBMSCs) is regulated by various factors, including bone morphogenetic proteins (BMPs), Notch, growth hormones and mitogen-activated protein kinases (MAPKs). Tribbles homolog 3 (TRIB3), a pseudokinase, plays an important...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Zhang, Cui, Hong, Fan-Fan, Wang, Cui-Cui, Li, Liang, Chen, Jian-Ling, Liu, Fei, Quan, Ren-Fu, Wang, Jin-Fu
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5583332/
https://ncbi.nlm.nih.gov/pubmed/28871113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10601-w
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