HIV-1 matrix protein p17 misfolding forms toxic amyloidogenic assemblies that induce neurocognitive disorders

Human immunodeficiency virus type-1 (HIV-1)-associated neurocognitive disorder (HAND) remains an important neurological manifestation that adversely affects a patient’s quality of life. HIV-1 matrix protein p17 (p17) has been detected in autoptic brain tissue of HAND individuals who presented early...

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Publicado en:Sci Rep
Autores principales: Zeinolabediny, Yasmin, Caccuri, Francesca, Colombo, Laura, Morelli, Federica, Romeo, Margherita, Rossi, Alessandro, Schiarea, Silvia, Ciaramelli, Carlotta, Airoldi, Cristina, Weston, Ria, Donghui, Liu, Krupinski, Jerzy, Corpas, Rubén, García-Lara, Elisa, Sarroca, Sara, Sanfeliu, Coral, Slevin, Mark, Caruso, Arnaldo, Salmona, Mario, Diomede, Luisa
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5583282/
https://ncbi.nlm.nih.gov/pubmed/28871125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10875-0
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