Astragaloside-IV prevents acute kidney injury and inflammation by normalizing muscular mitochondrial function associated with a nitric oxide protective mechanism in crush syndrome rats

BACKGROUND: Crush syndrome (CS) is a serious medical condition characterized by muscle cell damage resulting from decompression after compression (i.e., ischemia/reperfusion injury). A large number of CS patients develop cardiac failure, kidney dysfunction, and systemic inflammation, even when fluid...

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Bibliografiske detaljer
Udgivet i:Ann Intensive Care
Main Authors: Murata, Isamu, Abe, Yuji, Yaginuma, Yuka, Yodo, Kayako, Kamakari, Yuka, Miyazaki, Yurika, Baba, Daichi, Shinoda, Yuko, Iwasaki, Toru, Takahashi, Kunihiko, Kobayashi, Jun, Inoue, Yutaka, Kanamoto, Ikuo
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2017
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5583140/
https://ncbi.nlm.nih.gov/pubmed/28871521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13613-017-0313-2
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