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Design and reactivity of Ni-complexes using pentadentate neutral-polypyridyl ligands: Possible mimics of NiSOD

Superoxide plays a key role in cell signaling, but can be cytotoxic within cells unless well regulated by enzymes known as superoxide dismutases (SOD). Nickel superoxide dismutase (NiSOD) catalyzes the disproportion of the harmful superoxide radical into hydrogen peroxide and dioxygen. NiSOD has a u...

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Detalhes bibliográficos
Publicado no:J Inorg Biochem
Main Authors: Snider, Victoria G., Farquhar, Erik R., Allen, Mark, Abu-Spetani, Ayah, Mukherjee, Anusree
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5583021/
https://ncbi.nlm.nih.gov/pubmed/28750282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2017.07.005
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