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Brain-derived neurotrophic factor and airway fibrosis in asthma

Airway remodeling in asthma driven by inflammation involves proliferation of epithelial cells and airway smooth muscle (ASM), as well as enhanced extracellular matrix (ECM) generation and deposition, i.e., fibrosis. Accordingly, understanding profibrotic mechanisms is important for developing novel...

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Bibliographische Detailangaben
Veröffentlicht in:Am J Physiol Lung Cell Mol Physiol
Hauptverfasser: Freeman, Michelle R., Sathish, Venkatachalem, Manlove, Logan, Wang, Shengyu, Britt, Rodney D., Thompson, Michael A., Pabelick, Christina M., Prakash, Y. S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582935/
https://ncbi.nlm.nih.gov/pubmed/28522569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00580.2016
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