Brain-derived neurotrophic factor and airway fibrosis in asthma

Airway remodeling in asthma driven by inflammation involves proliferation of epithelial cells and airway smooth muscle (ASM), as well as enhanced extracellular matrix (ECM) generation and deposition, i.e., fibrosis. Accordingly, understanding profibrotic mechanisms is important for developing novel...

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Publicat a:Am J Physiol Lung Cell Mol Physiol
Autors principals: Freeman, Michelle R., Sathish, Venkatachalem, Manlove, Logan, Wang, Shengyu, Britt, Rodney D., Thompson, Michael A., Pabelick, Christina M., Prakash, Y. S.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582935/
https://ncbi.nlm.nih.gov/pubmed/28522569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00580.2016
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