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Brain-derived neurotrophic factor and airway fibrosis in asthma

Airway remodeling in asthma driven by inflammation involves proliferation of epithelial cells and airway smooth muscle (ASM), as well as enhanced extracellular matrix (ECM) generation and deposition, i.e., fibrosis. Accordingly, understanding profibrotic mechanisms is important for developing novel...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Freeman, Michelle R., Sathish, Venkatachalem, Manlove, Logan, Wang, Shengyu, Britt, Rodney D., Thompson, Michael A., Pabelick, Christina M., Prakash, Y. S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582935/
https://ncbi.nlm.nih.gov/pubmed/28522569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00580.2016
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