EET intervention on Wnt1, NOV, and HO-1 signaling prevents obesity-induced cardiomyopathy in obese mice

We have previously reported that epoxyeicosatrienoic acid (EET) has multiple beneficial effects on vascular function; in addition to its antiapoptotic action, it increases insulin sensitivity and inhibits inflammation. To uncover the signaling mechanisms by which EET reduces cardiomyopathy, we hypot...

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Опубликовано в: :Am J Physiol Heart Circ Physiol
Главные авторы: Cao, Jian, Singh, Shailendra P., McClung, John A., Joseph, Gregory, Vanella, Luca, Barbagallo, Ignazio, Jiang, Houli, Falck, John R., Arad, Michael, Shapiro, Joseph I., Abraham, Nader G.
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2017
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582926/
https://ncbi.nlm.nih.gov/pubmed/28576832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00093.2017
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