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Protein phosphatase 2C is responsible for VP-induced dephosphorylation of AQP2 serine 261

Aquaporin 2 (AQP2) trafficking is regulated by phosphorylation and dephosphorylation of serine residues in the AQP2 COOH terminus. Vasopressin (VP) binding to its receptor (V2R) leads to a cascade of events that result in phosphorylation of serine 256 (S256), S264, and S269, but dephosphorylation of...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Cheung, Pui W., Ueberdiek, Lars, Day, Jack, Bouley, Richard, Brown, Dennis
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582913/
https://ncbi.nlm.nih.gov/pubmed/28381458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00004.2017
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