Gender difference in kidney electrolyte transport. I. Role of AT(1a) receptor in thiazide-sensitive Na(+)-Cl(−) cotransporter activity and expression in male and female mice

We studied gender differences in Na(+)-Cl(−) cotransporter (NCC) activity and expression in wild-type (WT) and AT(1a) receptor knockout (KO) mice. In renal clearance experiments, urine volume (UV), glomerular filtration rate, absolute Na(+) (E(Na)) and K(+) (E(K)), and fractional Na(+) (FE(Na)) and...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Li, Jing, Hatano, Ryo, Xu, Shuhua, Wan, Laxiang, Yang, Lei, Weinstein, Alan M., Palmer, Lawrence, Wang, Tong
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582908/
https://ncbi.nlm.nih.gov/pubmed/28566500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00087.2017
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