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Cyp8b1 ablation prevents Western diet-induced weight gain and hepatic steatosis because of impaired fat absorption
Bile acids (BAs) are cholesterol derivatives that regulate lipid metabolism, through their dual abilities to promote lipid absorption and activate BA receptors. However, different BA species have varying abilities to perform these functions. Eliminating 12α-hydroxy BAs in mice via Cyp8b1 knockout ca...
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| Publicado no: | Am J Physiol Endocrinol Metab |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5582885/ https://ncbi.nlm.nih.gov/pubmed/28377401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00409.2016 |
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