The NLRP3 inflammasome contributes to sarcopenia and lower muscle glycolytic potential in old mice

The mechanisms underpinning decreased skeletal muscle strength and slowing of movement during aging are ill-defined. “Inflammaging,” increased inflammation with advancing age, may contribute to aspects of sarcopenia, but little is known about the participatory immune components. We discovered that a...

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Foilsithe in:Am J Physiol Endocrinol Metab
Main Authors: McBride, Marin Jane, Foley, Kevin P., D’Souza, Donna M., Li, Yujin E., Lau, Trevor C., Hawke, Thomas J., Schertzer, Jonathan D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Physiological Society 2017
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582883/
https://ncbi.nlm.nih.gov/pubmed/28536183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00060.2017
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