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Opposites attract in bispecific antibody engineering
Bispecific antibodies show great promise as intrinsic combination therapies, but often suffer from poor physiochemical properties, many times related to poor heterodimerization. De Nardis et al. identify specific electrostatic interactions that facilitate efficient heterodimerization, resulting in b...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5582862/ https://ncbi.nlm.nih.gov/pubmed/28864715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.H117.793497 |
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