CD14 is a key mediator of both lysophosphatidic acid and lipopolysaccharide induction of foam cell formation

Macrophage uptake of oxidized low-density lipoprotein (oxLDL) plays an important role in foam cell formation and the pathogenesis of atherosclerosis. We report here that lysophosphatidic acid (LPA) enhances lipopolysaccharide (LPS)-induced oxLDL uptake in macrophages. Our data revealed that both LPA...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: An, Dong, Hao, Feng, Zhang, Fuqiang, Kong, Wei, Chun, Jerold, Xu, Xuemin, Cui, Mei-Zhen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582834/
https://ncbi.nlm.nih.gov/pubmed/28705936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.781807
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados