Versican G1 domain enhances adenoviral-mediated transgene expression and can be modulated by inhibitors of the Janus kinase (JAK)/STAT and Src family kinase pathways

To examine the biochemical influences that may contribute to the success of gene therapy for ocular disorders, the role of versican, a vitreous component, in adenoviral-mediated transgene expression was examined. Versican is a large chondroitin sulfate-containing, hyaluronic acid-binding proteoglyca...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Akinfenwa, Patricia Y., Bond, Wesley S., Ildefonso, Cristhian J., Hurwitz, Mary Y., Hurwitz, Richard L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2017
Pynciau:
Glycobiology and Extracellular Matrices
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582833/
https://ncbi.nlm.nih.gov/pubmed/28684419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.773549
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