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Secondary structure prediction and structure-specific sequence analysis of single-stranded DNA

DNA sequence analysis by oligonucleotide binding is often affected by interference with the secondary structure of the target DNA. Here we describe an approach that improves DNA secondary structure prediction by combining enzymatic probing of DNA by structure-specific 5′-nucleases with an energy min...

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Autors principals: Dong, Fang, Allawi, Hatim T., Anderson, Todd, Neri, Bruce P., Lyamichev, Victor I.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC55824/
https://ncbi.nlm.nih.gov/pubmed/11470883
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