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Signatures derived from increase in SHARPIN gene copy number are associated with poor prognosis in patients with breast cancer

We report three signatures produced from SHARPIN gene copy number increase (GCN-Increase) and their effects on patients with breast cancer (BC). In the Metabric dataset (n = 2059, cBioPortal), SHARPIN GCN-Increase occurs preferentially or mutual exclusively with mutations in TP53, PIK3CA, and CDH1....

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Detalhes bibliográficos
Publicado no:BBA Clin
Main Authors: Ojo, Diane, Seliman, Maryam, Tang, Damu
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582379/
https://ncbi.nlm.nih.gov/pubmed/28879097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbacli.2017.07.004
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