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Increased Hemodynamic Load in Early Embryonic Stages Alters Myofibril and Mitochondrial Organization in the Myocardium

Normal blood flow is essential for proper heart formation during embryonic development, as abnormal hemodynamic load (blood pressure and shear stress) results in cardiac defects seen in congenital heart disease (CHD). However, the detrimental remodeling processes that relate altered blood flow to ca...

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Dades bibliogràfiques
Publicat a:Front Physiol
Autors principals: Midgett, Madeline, López, Claudia S., David, Larry, Maloyan, Alina, Rugonyi, Sandra
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582297/
https://ncbi.nlm.nih.gov/pubmed/28912723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00631
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