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Increased Hemodynamic Load in Early Embryonic Stages Alters Myofibril and Mitochondrial Organization in the Myocardium

Normal blood flow is essential for proper heart formation during embryonic development, as abnormal hemodynamic load (blood pressure and shear stress) results in cardiac defects seen in congenital heart disease (CHD). However, the detrimental remodeling processes that relate altered blood flow to ca...

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Detalles Bibliográficos
Publicado en:Front Physiol
Main Authors: Midgett, Madeline, López, Claudia S., David, Larry, Maloyan, Alina, Rugonyi, Sandra
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582297/
https://ncbi.nlm.nih.gov/pubmed/28912723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00631
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