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Paradoxical effect of IKKβ inhibition on the expression of E3 ubiquitin ligases and unloading‐induced skeletal muscle atrophy

We tested whether NF‐κB pathway is indispensable for the increase in expression of E3‐ligases and unloading‐induced muscle atrophy using IKKβ inhibitor IMD‐0354. Three groups of rats were used: nontreated control (C), 3 days of unloading/hindlimb suspension with (HS+IMD) or without (HS) IMD‐0354. Le...

詳細記述

保存先:
書誌詳細
出版年:Physiol Rep
主要な著者: Belova, Svetlana P., Shenkman, Boris S., Kostrominova, Tatiana Y., Nemirovskaya, Tatiana L.
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582258/
https://ncbi.nlm.nih.gov/pubmed/28839114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13291
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