The weak interdomain coupling observed in the 70 kDa subunit of human replication protein A is unaffected by ssDNA binding

Replication protein A (RPA) is a heterotrimeric, multi-functional protein that binds single-stranded DNA (ssDNA) and is essential for eukaryotic DNA metabolism. Using heteronuclear NMR methods we have investigated the domain interactions and ssDNA binding of a fragment from the 70 kDa subunit of hum...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Daughdrill, Gary W., Ackerman, Jennifer, Isern, Nancy G., Botuyan, Maria V., Arrowsmith, Cheryl, Wold, Marc S., Lowry, David F.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 2001
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55822/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11470885/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.15.3270
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