The weak interdomain coupling observed in the 70 kDa subunit of human replication protein A is unaffected by ssDNA binding

Replication protein A (RPA) is a heterotrimeric, multi-functional protein that binds single-stranded DNA (ssDNA) and is essential for eukaryotic DNA metabolism. Using heteronuclear NMR methods we have investigated the domain interactions and ssDNA binding of a fragment from the 70 kDa subunit of hum...

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Main Authors: Daughdrill, Gary W., Ackerman, Jennifer, Isern, Nancy G., Botuyan, Maria V., Arrowsmith, Cheryl, Wold, Marc S., Lowry, David F.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2001
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC55822/
https://ncbi.nlm.nih.gov/pubmed/11470885
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