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Delayed treatment with Chondroitinase ABC promotes sensorimotor recovery and plasticity after stroke in aged rats

Stroke is the dominant cause of sensorimotor disability that primarily affects the elderly. We now show that neuroplasticity and functional recovery after stroke is constrained by inhibitory chondroitin sulphates. In two blinded, randomised pre-clinical trials, degradation of chondroitin sulphate us...

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Detalhes bibliográficos
Publicado no:Brain
Main Authors: Soleman, Sara, Yip, Ping K., Duricki, Denise A., Moon, Lawrence D.F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581954/
https://ncbi.nlm.nih.gov/pubmed/22396394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/aws027
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