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Delayed intramuscular human neurotrophin-3 improves recovery in adult and elderly rats after stroke

There is an urgent need for a therapy that reverses disability after stroke when initiated in a time frame suitable for the majority of new victims. We show here that intramuscular delivery of neurotrophin-3 (NT3, encoded by NTF3 ) can induce sensorimotor recovery when treatment is initiated 24 h af...

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Detalhes bibliográficos
Publicado no:Brain
Main Authors: Duricki, Denise A., Hutson, Thomas H., Kathe, Claudia, Soleman, Sara, Gonzalez-Carter, Daniel, Petruska, Jeffrey C., Shine, H. David, Chen, Qin, Wood, Tobias C., Bernanos, Michel, Cash, Diana, Williams, Steven C. R., Gage, Fred H., Moon, Lawrence D. F.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4785394/
https://ncbi.nlm.nih.gov/pubmed/26614754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awv341
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