A carregar...
Lentiviral vectors encoding shRNAs efficiently transduce and knockdown LINGO-1 but induce an interferon response and cytotoxicity in CNS neurons
BACKGROUND: Knocking down neuronal LINGO-1 using short hairpin RNAs (shRNAs) might enhance axon regeneration in the CNS. Integration-deficient lentiviral vectors have great potential as a therapeutic delivery system for CNS injuries. However, recent studies have revealed that shRNAs can induce an in...
Na minha lista:
| Publicado no: | J Gene Med |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5581949/ https://ncbi.nlm.nih.gov/pubmed/22499506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jgm.2626 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|