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Normal and Cancerous Tissues Release extrachromosomal circular DNA (eccDNA) into the Circulation

Cell-free circulating linear DNA is being explored for non-invasive diagnosis and management of tumors and fetuses, the so-called liquid biopsy. Previously, we observed the presence of small extrachromosomal circular DNA (eccDNA), called microDNA, in the nuclei of mammalian tissues and cell lines. N...

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Bibliographic Details
Published in:Mol Cancer Res
Main Authors: Kumar, Pankaj, Dillon, Laura W., Shibata, Yoshiyuki, Jazaeri, Amir, Jones, David R., Dutta, Anindya
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581709/
https://ncbi.nlm.nih.gov/pubmed/28550083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-17-0095
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