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Entanglement of GSK-3β, β-catenin and TGF-β1 signaling network to regulate myocardial fibrosis

Nearly every form of the heart disease is associated with myocardial fibrosis, which is characterized by the accumulation of activated cardiac fibroblasts (CFs) and excess deposition of extracellular matrix (ECM). Although, CFs are the primary mediators of myocardial fibrosis in a diseased heart, in...

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Détails bibliographiques
Publié dans:J Mol Cell Cardiol
Auteurs principaux: Guo, Yuanjun, Gupte, Manisha, Umbarkar, Prachi, Singh, Anand Prakash, Sui, Jennifer, Force, Thomas, Lal, Hind
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581678/
https://ncbi.nlm.nih.gov/pubmed/28756206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2017.07.011
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