Statistical control of peptide and protein error rates in large-scale targeted DIA analyses

Liquid chromatography coupled to tandem mass spectrometry is the main method for high-throughput identification and quantification of peptides and inferred proteins. Within this field, data-independent acquisition (DIA) combined with peptide-centric scoring, exemplified by SWATH-MS, emerged as a sca...

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Detalhes bibliográficos
Publicado no:Nat Methods
Main Authors: Rosenberger, George, Bludau, Isabell, Schmitt, Uwe, Heusel, Moritz, Hunter, Christie, Liu, Yansheng, MacCoss, Michael J., MacLean, Brendan X., Nesvizhskii, Alexey I., Pedrioli, Patrick G. A., Reiter, Lukas, Röst, Hannes L., Tate, Stephen, Ting, Ying S., Collins, Ben C., Aebersold, Ruedi
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581544/
https://ncbi.nlm.nih.gov/pubmed/28825704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.4398
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