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NLRP3 inflammasome activation promotes inflammation-induced carcinogenesis in head and neck squamous cell carcinoma

BACKGROUND: NLRP3 inflammasome acts as a danger signal sensor that triggers and coordinates the inflammatory response. However, the roles of NLRP3 inflammasome in the tumorigenesis and development of cancer stem cells (CSCs) of squamous cell carcinoma of the head and neck (SCCHN) remain ambiguous. M...

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Detalles Bibliográficos
Publicado en:J Exp Clin Cancer Res
Main Authors: Huang, Cong-Fa, Chen, Lei, Li, Yi-Cun, Wu, Lei, Yu, Guang-Tao, Zhang, Wen-Feng, Sun, Zhi-Jun
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581464/
https://ncbi.nlm.nih.gov/pubmed/28865486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-017-0589-y
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