Loss of FMRP Impaired Hippocampal Long-Term Plasticity and Spatial Learning in Rats

Fragile X syndrome (FXS) is a neurodevelopmental disorder caused by mutations in the FMR1 gene that inactivate expression of the gene product, the fragile X mental retardation 1 protein (FMRP). In this study, we used clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associate...

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Detalles Bibliográficos
Publicado en:Front Mol Neurosci
Autores principales: Tian, Yonglu, Yang, Chaojuan, Shang, Shujiang, Cai, Yijun, Deng, Xiaofei, Zhang, Jian, Shao, Feng, Zhu, Desheng, Liu, Yunbo, Chen, Guiquan, Liang, Jing, Sun, Qiang, Qiu, Zilong, Zhang, Chen
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581399/
https://ncbi.nlm.nih.gov/pubmed/28894415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00269
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