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Loss of FMRP Impaired Hippocampal Long-Term Plasticity and Spatial Learning in Rats
Fragile X syndrome (FXS) is a neurodevelopmental disorder caused by mutations in the FMR1 gene that inactivate expression of the gene product, the fragile X mental retardation 1 protein (FMRP). In this study, we used clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associate...
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| Publicado no: | Front Mol Neurosci |
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| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5581399/ https://ncbi.nlm.nih.gov/pubmed/28894415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00269 |
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