Sirtuin 2 Deficiency Increases Bacterial Phagocytosis by Macrophages and Protects from Chronic Staphylococcal Infection

Sirtuin 2 (SIRT2) is one of the seven members of the family of NAD(+)-dependent histone deacetylases. Sirtuins target histones and non-histone proteins according to their subcellular localization, influencing various biological processes. SIRT2 resides mainly in the cytoplasm and regulates cytoskele...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Ciarlo, Eleonora, Heinonen, Tytti, Théroude, Charlotte, Herderschee, Jacobus, Mombelli, Matteo, Lugrin, Jérôme, Pfefferlé, Marc, Tyrrell, Beatrice, Lensch, Sarah, Acha-Orbea, Hans, Le Roy, Didier, Auwerx, Johan, Roger, Thierry
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581327/
https://ncbi.nlm.nih.gov/pubmed/28894448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01037
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