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Plasma Membrane Calcium ATPase 4 (PMCA4) co-ordinates Calcium and Nitric Oxide signaling in regulating Murine Sperm functional activity

Reduced sperm motility (asthenospermia) and resulting infertility arise from deletion of the Plasma Membrane Ca(2+)-ATPase 4 (Pmca4) gene which encodes the highly conserved Ca(2+) efflux pump, PMCA4. This is the major Ca(2+) clearance protein in murine sperm. Since the mechanism underlying asthenosp...

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Bibliographic Details
Published in:J Cell Physiol
Main Authors: Olli, Kristine E., Li, Kun, Galileo, Deni S., Martin-DeLeon, Patricia A.
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581300/
https://ncbi.nlm.nih.gov/pubmed/28247940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.25882
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