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Plasma Membrane Ca(2+)-ATPase 4 in Murine Epididymis: Secretion of Splice Variants in the Luminal Fluid and a Role in Sperm Maturation

Plasma membrane Ca(2+)-ATPase isoform 4 (PMCA4) is the primary Ca(2+) efflux pump in murine sperm, where it regulates motility. In Pmca4 null sperm, motility loss results in infertility. We have shown that murine sperm PMCA4b interacts with Ca(2+)/CaM-dependent serine kinase (CASK) in regulating Ca(...

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Detalhes bibliográficos
Main Authors: Patel, Ramkrishna, Al-Dossary, Amal A., Stabley, Deborah L., Barone, Carol, Galileo, Deni S., Strehler, Emanuel E., Martin-DeLeon, Patricia A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for the Study of Reproduction, Inc. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076351/
https://ncbi.nlm.nih.gov/pubmed/23699388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.113.108712
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