Chloroquine improves the response to ischemic muscle injury and increases HMGB1 following arterial ligation

OBJECTIVE: We have previously shown that exogenous administration of the nuclear protein High Mobility Group Box 1 (HMGB1) improves angiogenesis following tissue ischemia. Antagonizing HMGB1 prolongs muscle necrosis and deters regeneration. In this study, we evaluated HMGB1 expression in peripheral...

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Detalhes bibliográficos
Publicado no:J Vasc Surg
Main Authors: Xu, Jun, Cui, Xiangdong, Li, Jiehua, Koutakis, Panagiotis, Pipinos, Iraklis, Tzeng, Edith, Chen, Alex, Sachdev, Ulka
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581296/
https://ncbi.nlm.nih.gov/pubmed/28259568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jvs.2017.01.021
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