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The association of single nucleotide polymorphisms in the oxytocin receptor and G protein-coupled receptor kinase 6 (GRK6) genes with oxytocin dosing requirements and labor outcomes

BACKGROUND: Oxytocin is a potent uterotonic agent that is widely used for induction and augmentation of labor. Oxytocin has a narrow therapeutic index and the optimal dosing for any individual woman varies widely. OBJECTIVE: The objective of this study was to determine if genetic variation in the ox...

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Detalhes bibliográficos
Publicado no:Am J Obstet Gynecol
Main Authors: GROTEGUT, Chad A, NGAN, Emily, GARRETT, Melanie E, MIRANDA, Marie Lynn, ASHLEY-KOCH, Allison E, SWAMY, Geeta K
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581254/
https://ncbi.nlm.nih.gov/pubmed/28526450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2017.05.023
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