Selective Inhibitors of Nuclear Export (SINE) compounds block proliferation and migration of triple negative breast cancer cells by restoring expression of ARRDC3

Arrestin-related domain-containing protein-3 (ARRDC3) is one of 6 mammalian arrestins, which suppresses metastasis by inducing degradation of phosphorylated β2-adrenergic receptor (β2 AR) and integrin β4 (ITG β4). Our previous studies demonstrated that expression of ARRDC3 is epigentically silenced...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Soung, Young Hwa, Kashyap, Trinayan, Nguyen, Thalia, Yadav, Garima, Chang, Hua, Landesman, Yosef, Chung, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581083/
https://ncbi.nlm.nih.gov/pubmed/28881784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17987
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