Whole tumor RNA-sequencing and deconvolution reveal a clinically-prognostic PTEN/PI3K-regulated glioma transcriptional signature

The concept that solid tumors are maintained by a productive interplay between neoplastic and non-neoplastic elements has gained traction with the demonstration that stromal fibroblasts and immune system cells dictate cancer development and progression. While less studied, brain tumor (glioma) biolo...

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Udgivet i:Oncotarget
Main Authors: Pan, Yuan, Bush, Erin C., Toonen, Joseph A., Ma, Yu, Solga, Anne C., Sims, Peter A., Gutmann, David H.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581044/
https://ncbi.nlm.nih.gov/pubmed/28881745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17193
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