Whole tumor RNA-sequencing and deconvolution reveal a clinically-prognostic PTEN/PI3K-regulated glioma transcriptional signature

The concept that solid tumors are maintained by a productive interplay between neoplastic and non-neoplastic elements has gained traction with the demonstration that stromal fibroblasts and immune system cells dictate cancer development and progression. While less studied, brain tumor (glioma) biolo...

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Pubblicato in:Oncotarget
Autori principali: Pan, Yuan, Bush, Erin C., Toonen, Joseph A., Ma, Yu, Solga, Anne C., Sims, Peter A., Gutmann, David H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581044/
https://ncbi.nlm.nih.gov/pubmed/28881745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17193
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