Associations of α-thalassemia and BCL11A with stroke in Nigerian, United States, and United Kingdom sickle cell anemia cohorts

α-Thalassemia and the BCL11A rs1427407 T allele are commonly observed in sickle cell anemia (SCA) patients and are associated with reduced hemolysis and higher hemoglobin F levels, respectively. We investigated whether a high-risk genetic profile, defined as SCA patients who did not inherit either α...

詳細記述

保存先:
書誌詳細
出版年:Blood Adv
主要な著者: Saraf, Santosh L., Akingbola, Titilola S., Shah, Binal N., Ezekekwu, Chinedu A., Sonubi, Omowunmi, Zhang, Xu, Hsu, Lewis L., Gladwin, Mark T., Machado, Roberto F., Cooper, Richard S., Gordeuk, Victor R., Tayo, Bamidele O.
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2017
主題:
Global Advances
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5580997/
https://ncbi.nlm.nih.gov/pubmed/28868518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017005231
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