Associations of α-thalassemia and BCL11A with stroke in Nigerian, United States, and United Kingdom sickle cell anemia cohorts

α-Thalassemia and the BCL11A rs1427407 T allele are commonly observed in sickle cell anemia (SCA) patients and are associated with reduced hemolysis and higher hemoglobin F levels, respectively. We investigated whether a high-risk genetic profile, defined as SCA patients who did not inherit either α...

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Dades bibliogràfiques
Publicat a:Blood Adv
Autors principals: Saraf, Santosh L., Akingbola, Titilola S., Shah, Binal N., Ezekekwu, Chinedu A., Sonubi, Omowunmi, Zhang, Xu, Hsu, Lewis L., Gladwin, Mark T., Machado, Roberto F., Cooper, Richard S., Gordeuk, Victor R., Tayo, Bamidele O.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2017
Matèries:
Global Advances
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5580997/
https://ncbi.nlm.nih.gov/pubmed/28868518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017005231
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