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Osteopontin regulates the cross-talk between phosphatidylcholine and cholesterol metabolism in mouse liver

Osteopontin (OPN) is involved in different liver pathologies in which metabolic dysregulation is a hallmark. Here, we investigated whether OPN could alter liver, and more specifically hepatocyte, lipid metabolism and the mechanism involved. In mice, lack of OPN enhanced cholesterol 7α-hydroxylase (C...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Nuñez-Garcia, Maitane, Gomez-Santos, Beatriz, Buqué, Xabier, García-Rodriguez, Juan L., Romero, Marta R., Marin, Jose J. G., Arteta, Beatriz, García-Monzón, Carmelo, Castaño, Luis, Syn, Wing-kin, Fresnedo, Olatz, Aspichueta, Patricia
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5580904/
https://ncbi.nlm.nih.gov/pubmed/28754826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M078980
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