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Osteopontin regulates the cross-talk between phosphatidylcholine and cholesterol metabolism in mouse liver
Osteopontin (OPN) is involved in different liver pathologies in which metabolic dysregulation is a hallmark. Here, we investigated whether OPN could alter liver, and more specifically hepatocyte, lipid metabolism and the mechanism involved. In mice, lack of OPN enhanced cholesterol 7α-hydroxylase (C...
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| Publicado no: | J Lipid Res |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Biochemistry and Molecular Biology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5580904/ https://ncbi.nlm.nih.gov/pubmed/28754826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M078980 |
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