Dietary PUFAs attenuate NLRP3 inflammasome activation via enhancing macrophage autophagy

Dietary PUFAs reduce atherosclerosis and macrophage inflammation, but how nucleotide-binding oligomerization domain leucine-rich repeat-containing receptor protein (NLRP3) inflammasome activation and autophagy influence PUFA-mediated atheroprotection is poorly understood. We fed Ldlr(−/−) mice diets...

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Dettagli Bibliografici
Pubblicato in:J Lipid Res
Autori principali: Shen, Lulu, Yang, Yan, Ou, Tiantong, Key, Chia-Chi C., Tong, Sarah H., Sequeira, Russel C., Nelson, Jonathan M., Nie, Yan, Wang, Zhan, Boudyguina, Elena, Shewale, Swapnil V., Zhu, Xuewei
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2017
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5580895/
https://ncbi.nlm.nih.gov/pubmed/28729463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M075879
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