HIT'nDRIVE: patient-specific multidriver gene prioritization for precision oncology

Prioritizing molecular alterations that act as drivers of cancer remains a crucial bottleneck in therapeutic development. Here we introduce HIT'nDRIVE, a computational method that integrates genomic and transcriptomic data to identify a set of patient-specific, sequence-altered genes, with suff...

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Dettagli Bibliografici
Pubblicato in:Genome Res
Autori principali: Shrestha, Raunak, Hodzic, Ermin, Sauerwald, Thomas, Dao, Phuong, Wang, Kendric, Yeung, Jake, Anderson, Shawn, Vandin, Fabio, Haffari, Gholamreza, Collins, Colin C., Sahinalp, S. Cenk
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2017
Soggetti:
Method
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5580716/
https://ncbi.nlm.nih.gov/pubmed/28768687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.221218.117
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