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Tropomodulin 1 controls erythroblast enucleation via regulation of F-actin in the enucleosome

Biogenesis of mammalian red blood cells requires nuclear expulsion by orthochromatic erythoblasts late in terminal differentiation (enucleation), but the mechanism is largely unexplained. Here, we employed high-resolution confocal microscopy to analyze nuclear morphology and F-actin rearrangements d...

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Dettagli Bibliografici
Pubblicato in:Blood
Autori principali: Nowak, Roberta B., Papoin, Julien, Gokhin, David S., Casu, Carla, Rivella, Stefano, Lipton, Jeffrey M., Blanc, Lionel, Fowler, Velia M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5580276/
https://ncbi.nlm.nih.gov/pubmed/28729432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-05-787051
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