Tropomodulin 1 controls erythroblast enucleation via regulation of F-actin in the enucleosome

Biogenesis of mammalian red blood cells requires nuclear expulsion by orthochromatic erythoblasts late in terminal differentiation (enucleation), but the mechanism is largely unexplained. Here, we employed high-resolution confocal microscopy to analyze nuclear morphology and F-actin rearrangements d...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Nowak, Roberta B., Papoin, Julien, Gokhin, David S., Casu, Carla, Rivella, Stefano, Lipton, Jeffrey M., Blanc, Lionel, Fowler, Velia M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2017
Assuntos:
Red Cells, Iron, and Erythropoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5580276/
https://ncbi.nlm.nih.gov/pubmed/28729432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-05-787051
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