Tropomodulin 1 controls erythroblast enucleation via regulation of F-actin in the enucleosome

Biogenesis of mammalian red blood cells requires nuclear expulsion by orthochromatic erythoblasts late in terminal differentiation (enucleation), but the mechanism is largely unexplained. Here, we employed high-resolution confocal microscopy to analyze nuclear morphology and F-actin rearrangements d...

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Detalles Bibliográficos
Publicado en:Blood
Main Authors: Nowak, Roberta B., Papoin, Julien, Gokhin, David S., Casu, Carla, Rivella, Stefano, Lipton, Jeffrey M., Blanc, Lionel, Fowler, Velia M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2017
Assuntos:
Red Cells, Iron, and Erythropoiesis
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5580276/
https://ncbi.nlm.nih.gov/pubmed/28729432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-05-787051
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